Sentence examples for enhancing its affinity from inspiring English sources

HSP90α and HSP72 work together as the only two essential components of the five-protein system for allowing hGRα to bind the incoming steroid hormone by enhancing its affinity for the ligand [6].

Finally, RanBP3 modulates the substrate selectivity of CRM1, enhancing its affinity for the HIV-1 Rev NES while decreasing that for Spn1 [23].

Binding of a unique heparin pentasaccharide to antithrombin III (AT-III) induces a conformation change in AT-III enhancing its affinity for thrombin and coagulation factors IXa and Xa.

To study the impact of CA on innate immune activation, the authors generated a mutant HIV-2 in which the cyclophilin-binding loop of the CA protein partially resembles that of HIV-1, thereby greatly enhancing its affinity for CypA (HIV-2 affinity enhanced capsid; HIVac-2, Fig. 4).

Although no obvious PIP box has been identified, Mgs1 interacts with PCNA (Hishida et al. 2006), and it harbours an N-terminal UBZ domain that selectively enhances its affinity for ubiquitin PCNA fusions in vivo and in vitro, with a marked preference for longer chains (Saugar et al. 2012).

This study investigates the doping of CTA with ionic liquids (ILs) to reduce the crystallinity of the CTA and enhance its affinity with CO2, thus increasing CO2 permeability and CO2/light gas selectivity.

Small angle neutron scattering is used to study the simultaneous adsorption of toluene and water vapor by a commercial high surface area carbon, oxidized to enhance its affinity for polar molecules.

Interestingly, the Kd that was calculated from the aptasensor signal showed a lower value implying that the anchoring of the aptamer on the Au surface enhanced its affinity to ATX.

Using selection from synthetic combinatorial libraries, we enhanced its affinity by > 100-fold, resulting in variants with Kd as low as 180 pM with no detectable loss of binding specificity.

It is known that processing of VEGF-D through cleavage occurs in the embryonic mouse lung, a step that greatly enhances its affinity for its receptors KDR and FLT4 [47].

Recently, Zondlo et al. showed that mutation of Pro27Ser in the p5317 28 peptide enhanced its affinity for MDM2 because the mutation increased the α-helical property of the p5317 28 peptide [32].