Sentence examples for enhancing its activity from inspiring English sources
Trp53inp1 is an anti-proliferative protein within the p53 pathway, being transcriptionally activated by p53 and enhancing its activity upon its responsive genes, that is, p21 (Okamura et al, 2001; Tomasini et al, 2001, 2002).
Trypsin could activate proPPO to PPO by cleaving propeptide from proPPO, thereby enhancing its activity (Benjakul et al. [2005]).
Importantly, genetic activation of the mt-sAC pathway stimulates COX phosphorylation, thereby enhancing its activity and correcting mitochondrial dysfunction in COX deficient cells.
Here, we have attempted to further understand the role of SIRT1 in pancreatic β-cells by determining whether enhancing its activity affects β-cell function in vivo in conditions of decreased β-cell function selectively mediated by fat.
The kinetic and thermodynamic parameters of wheat β-amylase (WBA) were characterized and various additives were evaluated for enhancing its activity and thermostability.
MYLK is the myosin light chain kinase, a dedicated calcium-dependent kinase that phosphorylates a specific site on the regulatory light chain of the myosin, enhancing its activity.
Based on the findings that entrapment of TMP in chitosan/alginate nanoparticles enhanced its activity, it was assessed whether active targeting of the nanoparticles to cell-surface receptors could further enhance this effect.
Hence, we conclude that Bmi1 and Ring1A form an active heterodimeric E3 ubiquitin ligase, where Ring1A is the active component and Bmi1 greatly enhances its activity.
Moreover, bortezomib might also stabilise the active caspase-8 fragment to enhance its activity as suggested by recent reports that provided evidence for its regulation through ubiquitination and degradation.
This suggests that in tumors where Notch1 is activated Lfng insertions can cooperate to enhance its activity.
When activated by the reactive oxygen species, BiP enhances its activity as a folding molecular chaperone, keeping proteins apart.
