Sentence examples for enhancing downstream from inspiring English sources

By efficiently enhancing downstream signaling of HGF pathways, the cellular activities and behaviors were activated to contribute to LG branching morphogenesis.

It is possible that the over-expression of cleaved, mature forms of growth factors by the transplanted cells is enough to prevent, inhibit or counteract neurotrophic action at the p75NTR by enhancing activation and/or upregulation of TrkRs, enhancing downstream neurotrophic effects.

These findings indicate that glucose metabolic signaling may synergize with Runx2 regulation of the Akt pathway, affecting post-translational modifications and enhancing downstream targets associated with cell survival.

Ionic liquid pretreatment is a promising method for biomass preparation that causes the structure of the cellulose to change from mostly crystalline to a mixture of cellulose II and amorphous cellulose [ 37], thereby enhancing downstream enzymatic hydrolysis [ 37, 38].

The key finding suggested that byproducts from biological pretreatment play important roles in enhancing downstream hydrolysis, which might be attributable to hydrolytic enzymes and iron-reducing compounds produced by I. lacteus.

IFs fulfill dual roles in apoptosis by modulating events upstream of caspase activation, providing resistance to apoptosis initiation and by enhancing downstream caspase-mediated proteolysis to facilitate the execution of cell death (Marceau et al., 2007).

Inside-out regulation of αIIbβ3 activation was also enhanced downstream of GPVI stimulation.

The second encompasses enhanced downstream pathways of PFL through overexpression of the formate hydrogen lyase (FHL) complex.

It should be noted that although the GmPHD2 had transcriptional suppression activity, it still can enhance downstream gene expressions.

While disrupting the PHD domain at physiologically relevant levels clearly results in defective JNK activation and apoptosis (Figures 5 and Figure 8 9, respectively), we and others have shown that overexpressing MEKK1 with a mutated PHD at high levels results in activation of and possibly enhanced downstream signaling [14].

Moreover, previous studies have demonstrated that CD44v6 interacts with c-Met to enhance downstream MET activation.