Thus, increased cell firing specifically enhances stimulus-secretion coupling of L-type Ca2+ channels in chromaffin cells in situ.
Will neurons be tuned to the enhancing stimulus?
This means that those stimulus properties that elicit reflexive attention (such as e.g., color or size) enhance stimulus recognition.
This is because a larger network response to the attended locations would suggest increased processing of the attended locations (to enhance stimulus information).
Normalization with MPH of reduced activation in typical frontoparietal regions of saliency processing and performance monitoring is consistent with the dopamine-deficiency hypothesis of ADHD given that dopamine agonists enhance stimulus salience (73).
The basic assumption, illustrated in Fig. 5A is that the P1 reflects an inhibitory filter (established synchronously in a parallel distributed network) during early categorization that is generated to enhance stimulus processing by increasing the SNR in task relevant networks.
These results suggest that, on these measures, motivational incentives have similar effects in children with ADHD as typically developing CTRLs and have additive effects with stimulant medication, enhancing stimulus salience and allocation of attentional resources during response inhibition.
Formerly iron deficient adult rats showed enhanced stimulus-response learning in the context of competing spatial/distal cue information, a finding suggestive of reduced hippocampal functional influence.
Top-down projections from the frontal eye field to visual area V4 can enhance stimulus-related activity, which emphasizes the importance of high level mechanisms [ 21, 25].
We also demonstrate that RASopathy-causing RRAS mutations are activating and promote signalling perturbation by enhancing stimulus-dependent MEK, ERK and, at a lower extent, AKT phosphorylation.
Although the precise reactive species quenched by these antioxidants (and their associated rates) are not well-defined, a causal role for elevated ROS levels in cancer-cell death has previously been inferred based on the ability of antioxidant molecules to prevent toxicity when co-treated with ROS-enhancing stimuli.
