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Analysis of genes modulated by the AZD6244 TRAIL association confirmed enhancement of the functions 'cell death' and 'apoptosis' (Supplementary Figures S8a and b and Supplementary Table S4).
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There are also experimental data about enhancement of the function of macrophages and the response of CD8+ T cells at low-dose exposure.
Whether a pathological condition that inhibits one isoform exerts the same effect on other isoforms or leads to "compensatory" enhancement of the function of others?
Salmond said: "Discussions will take place with Hewlett-Packard in terms of the protection and indeed the enhancement of the headquarter functions that will remain in Erskine".
Hence, it can be considered that enhancement of the immune functions contributes to the primary prevention of infectious illness, incidence of malignancy and autoimmune diseases in the elderly stage.
However, in view of the considerable errors involved in the normalization procedure it remains questionable whether this represents a true functional enhancement of the transporter function.
The differential changes could potentially be related to the normal function of HTT through the effects of increased overall huntingtin expression and thus enhancement of the normal function.
Thus, the benefits obtained after attachment to the cell surface would be restricted to the local enhancement of the inhibitory function of the viral IFNα/βBP and the abrogation of its GAG binding properties leads to a protein which is no longer able to control the IFN-I response during infection.
Most interestingly, via KP and electroabsorption measurements of the built-in potential on polymer/conductor and conductor/polymer/conductor structures, we demonstrate that a plasma-induced enhancement of the work function is "frozen in" by the application of a polymer semiconductor layer over the plasma-treated surfaces and can be made to last for years by proper device encapsulation.
This event leads to enhancement of the cytotoxic function of tumor necrosis factor [6]. Overexpressed WOX1 alone induces death of L929 in a caspase-independent manner [6].
The phospholamban knockout model is one of the few reported mouse models, where genetic manipulation produces enhancement of the cardiac function instead of pathological developments and failure.
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