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Further enhancement of expression is obtained by suing synthetic, codon-optimized cDNAs to express the encoded micro-dystrophin protein.
In conclusion, we have shown that CA XII is frequently expressed in invasive breast carcinoma and that focal enhancement of expression can be observed adjacent to areas of necrosis, supporting the notion that CA XII is a hypoxia regulated gene in vivo.
This anthocyanin production results from expression of the transgenes and the resulting activation (or enhancement) of expression of 13 endogenous anthocyanin biosynthesis genes that are silenced or expressed at low levels in wild-type rice endosperm.
On the basis of our study, the polyQ toxicity-enhancing phenotype in pqe-1 mutants could be caused by the enhancement of expression of Htn-Q150 in ASH neurons.
DNA array analysis showed specific enhancement of expression of muscle cell genes, supporting our conclusion that spermine induces differentiation of muscle cells in vitro.
Surprisingly, knocking down CBP resulted in enhancement of expression of other HIF-1α regulated genes, including VEGF, PGK and LDHA.
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As shown in Figure 5C, treatment of U87 cells with 125b-AS resulted in the reduction of Bcl-2 expression and enhancement of Bax expression.
Normally the enhancement of miRNA expression inhibits target mRNA expression, but it could also facilitate target mRNA expression [ 16, 17].
Thus, enhancement of DR expression on cell surface could enhance cancer surveillance.
Another possible explanation for the splicing-mediated enhancement of gene expression is that splicing mainly enhances the later rounds of transcription.
HpD-PDT could induce the enhancement of APE1 expression, and Ad5/F35-APE1 Ad5/F35-APE1efficiently knock down the upregulation of APE1 expresiRNA inducouldy PDT comparefficiently control group).
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