Setting aside these rather tangled socio-cultural questions, another query arises: How did boob-enhancement fever start anyway?
T1 FS TSE contrast-enhanced series showed enhancement of the lesion Open image in new window Fig. 14 a A 6-week-old boy with fever.
These findings potentially offer an alternative role of antibody-dependent-enhancement (ADE) induced plasma leakage in dengue hemorrhagic fever (DHF).
It was shown that syndromic surveillance detected the dengue fever outbreak several weeks before clinical surveillance, allowing quick and effective enhancement of vector control within the armed forces.
It also shows antibody-dependent enhancement of growth in human monocytes that is a serious risk factor in hemorrhagic fever [ 44].
DENV: Dengue virus; DF: Dengue fever; DHF: Dengue hemorrhagic fever; DSS: Dengue shock syndrome; ADE: Antibody-dependent enhancement; CDC Center for Disease Control and Preventionn; ELISA: Enzyme-linked immunosorbent assay; NIDRS: The Notifiable Infectious Disease Report System BII: Breteau index.
Through a mechanism known as immune enhancement, sequential infections with certain dengue viruses set the stage for a far more serious complication, dengue hemorrhagic fever (DHF) and dengue shock syndrome, so that having uncomplicated DF can presage having DHF (1).
An enhancement that may be useful in automated medical record systems, but not in claims based systems, is to require fever (measured value, not ICD9 code) to be part of the definition of a lower respiratory infection.
Furthermore, the nonneutralizing antibodies are known to facilitate viral infection, termed antibody-dependent enhancement (ADE), which is the pathogenic basis of feline infectious peritonitis virus (FIPV, a type II coronavirus), dengue hemorrhagic fever, and other viruses (34 – 37, 37 ).
