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In conjunctional with this conceptual shift, technologic advances in DNA sequencing techniques have dramatically enhanced whole genome or whole exome sequencing capacity.
A reader must look attentively at every detail in the frame, each telling her something small and discrete; then, quite suddenly, the details cohere, and the photo transforms into an enhanced whole.
In the background story, their human subjects had been disembodied and transformed by technology into a new enhanced whole.
Enhanced whole body computed tomography demonstrated systemic lymphadenopathy, hepatosplenomegaly, renal enlargement and anasarca.Bone marrow biopsy revealed a hyperplastic marrow with megakaryocytic hyperplasia and mild reticulin fibrosis.
Lower body weight in draggen males was accompanied by general metabolic alterations, including enhanced whole body energy expenditure and glucose tolerance, which together potentially contribute to the leaner phenotype.
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Long lived dwarf mice that are deficient in or resistant to growth hormone are hypoinsulinemic and exhibit enhanced whole-animal insulin sensitivity [34], [35], [36].
We have previously showed that gp120 IIIB enhanced whole-cell outward K+ currents in cultured rat microglia.
Sydow et al. [ 39] reported enhanced whole-body insulin sensitivity in transgenic mice overexpressing dimethylarginine dimethylaminohydrolase (DDAH), an enzyme responsible for the predominant pathway of ADMA degradation [ 40].
Other studies provided evidence that inhibition of ceramide de novo synthesis with myriocin improved glucose homeostasis and enhanced whole-body insulin responsiveness in rodent models of type 2 diabetes [ 23].
In common with mice that lack FMO1, FMO2 and FMO4, mice that lack FMO5 exhibit enhanced whole-body energy expenditure and REE, but have increased RER, indicating a switch from fat to carbohydrate oxidation.
The exogenous glucose infusion rate required to maintain euglycemia under clamp conditions was markedly higher in FGF21-Tg mice than in wild-type mice, demonstrating enhanced whole-body insulin sensitivity.
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