Farwell, K. D. et al. Enhanced utility of family-centered diagnostic exome sequencing with inheritance model-based analysis: results from 500 unselected families with undiagnosed genetic conditions.
The chapter also presents the type of biosensors, isolation and production of recombinant antibodies for use in the detection system, and engineering antibodies for enhanced utility in biosensor system.
Nevertheless, in the development of CPRs for application in clinical practice, it may be preferable for a certain amount of information to be sacrificed in the interests of enhanced utility and ease of use in daily clinical practice.
Currently, several rapidly evolving regions of the Salmonella chromosome are under investigation for their utility for enhanced subtyping of highly homogeneous Salmonella strains associated with foodborne outbreaks.
Patient chart review determined subjects with diagnosis of Cushing's syndrome or disease, and assay's clinical diagnostic sensitivity of 100% and specificity of 92% when the cutoff value was 70 ng/dL.The improved LC-MS/MS method is sensitive and specific with enhanced analytical performance and clinical diagnostic utility for screening Cushing's syndrome.
To evaluate whether the enhanced sensitivity of this method has utility for organisms with much larger genomes, we simulated 'rare single locus' hits in a substantially larger library by creating a superpool containing 5 μL of a single positive BAC clone and 3200 ([25 × 384]/3) negative BAC clones of 15 μL each.
This protein is also known to exhibit micro-heterogeneity [7], [12], [13], [14], [15] in both human plasma and urine, however the study of this phenomena for potentially enhanced clinical utility is lacking.
The hybrid crosslinking and fabrication approach offers potential utility for development of implantable tissue-engineered cell-carrier constructs with enhanced bio-functional properties.
Exhibiting enhanced total flux in Pd2+ enriched areas, palladium chemiluminescent probe (PCL) may afford potential utility for detecting Pd2+ in vitro, in cellulo and in vivo.
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