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It is to explore aspects of the abuse, including the psychological problems of the abusers and the "circumstances which enhanced the vulnerability of the victims," according to a statement from the conference.
We demonstrated that astrocytes under conditions of LPS stress released SVs, which enhanced the vulnerability of DA neurons to neurotoxin.
When we increased the miR-34a levels in astrocytic SVs without LPS stimulation by transfecting astrocytes with pre-miR-34a, we found that those SVs still enhanced the vulnerability of DA neurons to low concentrations of neurotoxins, leading to an increased percentage of apoptotic cells.
Maternal malnutrition increased this unbalance and probably through that way, enhanced the vulnerability of fetal and adult islets, as reported previously [16], [17].
The knockdown or pharmacological inhibition of Sirtuin-1 enhanced the vulnerability of human cells to metabolic stress, unless they were stimulated to undergo autophagy by treatment with rapamycin or p53 inhibition.
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In fact, the study shows that it is problematic to talk about "post" traumatic stress, given that stressful experiences of everyday violence (such as poverty, gender-based violence, and discrimination) continue to happen to Quechua women, a situation that appears to enhance the vulnerability to enhanced symptoms of distress for some people, as indicated by the findings of this study.
This excess freshwater discharge is low in total alkalinity and reduces the buffering capacity of surface waters and enhances the vulnerability of the estuary to further reductions in pH.
In contrast, the decreased nonenzymatic antioxidant reserve in the fetal red blood cell and plasma compartments after preterm labor and delivery would enhance the vulnerability to free radical damage of the preterm neonate.
One set of arguments appeals to the ways in which work-conditionality can enhance the vulnerability of citizens to exploitation or other forms of injustice and/or generate or exacerbate other inequities between citizens.
A number of socioeconomic factors along with geographical location enhance the vulnerability of individuals and communities in the study area and relentlessly undermine the struggle of people to minimize or cope with their vulnerabilities by undertaking adaptive measures.
Altogether, our results suggested that under stress conditions, such as LPS stimulation, increased levels of miR-34a in astrocytic SVs can be transported into DA neurons, where they enhance the vulnerability of the neurons to neurotoxins by targeting the anti-apoptotic protein Bcl-2.
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