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Most INOT studies employ cross-sectional designs despite the enhanced statistical power and reduction in error variance associated with individual differences characteristic of within-subject designs.
Our methods clearly show enhanced statistical power over existing methods for a wide range of population-attributable risk, percentage of disease-contributing rare variants, and proportion of rare alleles working in different directions.
Advantages are the greater precision of the estimates and the enhanced statistical power.
Such an approach enables to differentiate between interpatient and intrapatient variability, which results in enhanced statistical power to identify factors influencing PK.
A major strength of this study is the enlarged sample size, as compared to the previous meta-analysis, and we added 17 newly published case control studies, which provides enhanced statistical power and offers more precise and reliable effect estimates.
The large number of neurons simultaneously recorded, as well as the long recording durations (1 h or more) enhanced statistical power, allowing many connections to be identified that would have otherwise gone undetected.
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Sample size (dogs with both genotype and phenotype), sample selection from the available population, inclusion of different dogs in the linkage studies, GWAS and fine mapping (each of which only included a subset of common dogs), marker density and distribution, and marker informativeness each both enhanced and limited the statistical power of the current study.
In step 2, we extended the original multivariate PSC algorithm of Kim et al. [ 16] in two ways to construct the enhanced ribosomal cluster C ribo with greater statistical power and precision.
Statistical power determines whether we accurately conclude if there is an effect or not.
Statistical power.
6. Statistical power .
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