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Efforts are continuing to find novel bacteriocins with enhanced specificity and potency.
The kinase inhibitors with enhanced specificity and improved pharmacokinetics have been considered for design and development of anticancer agents.
We envisage these insights will open new avenues for further reductions in Cas9's ribose dependency and the generation of fully RNA-free endonucleases with novel properties, such as enhanced specificity and stability, which could be desirable when taking programmable guided nucleases into therapeutic settings.
Further evaluation of the effects of signal-smart viruses on host cell biology improves our understanding about the mechanism of the virus-host relationship and opens new horizons in using these biological agents in detection and targeting cancer cells with enhanced specificity and efficiency.
High-throughput targeted RNA capture is a novel approach that offers enhanced specificity and scale over more traditional validation methods such as RT-PCR.
Importantly, for both ultrasound and chest X-ray, changing the unit of analysis from lung to lung region reduced sensitivity but enhanced specificity, and gave more precise estimates of accuracy (narrower CIs).
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Adoptive immunotherapy has rapidly evolved to harness modern genetic techniques to create T cells with enhanced specificity, efficacy and safety.
This three-pronged approach has the expected outcome of producing novel stimulation treatments with enhanced specificity, plasticity, and efficacy.
Due to the enhanced specificity, potency and pharmacokinetics of MK-2206 we focused our subsequent studies on this inhibitor.
These results indicate that CSA is involved in the adhesion of the recrudescent parasite to the placenta tissue and suggest that the recrudescent P. berghei expanding during pregnancy displays enhanced specificity to the placenta and consequently may induce a specific host response to the pregnancy-associated parasite.
Previous research with LNA in other applications has shown interesting properties for molecular hybridization including enhanced specificity in allele-specific PCR.
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