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A route to achieve improved sensitivity, exploiting the hydrophilic/hydrophobic properties of the host + glucose system for enhanced selective binding to the hydrophobic boron doped graphene support is discussed.
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Hydrophobicity and polymer porosity may enhance selective binding of organic high explosive analytes, which can be further enhanced in molecularly imprinted polymers [ 5, 35 ].
While this study does not represent a useful capping agent in itself, we have demonstrated a principle that could be combined in peptides with other residues that enhance selective binding to the amyloid in question.
Computational mutational free energy analyses also revealed a number of possible single-site mutations to GID which might enhance its selective binding to α4β2 over α7.
Poly-glutamic and poly-aspartic acid tracts feature in many NLS (nuclear localisation signal) proteins [ 39], and it has been suggested that both basic karyophilic and acidic clusters can enhance their selective binding to transport machinery components [ 40].
Moreover, the deployment of molecular recognition probe on the nanostructures for the selective binding have enhanced the selectivity and detection ability.
Here, we demonstrate that the conjugate of the BLM carbamoylmannose moiety with Cy5** showed tumor cell selective binding and also enhanced cellular uptake in most cancer cell lines.
Shaked et al. [ 13] reported that the selective binding of plasminogen to PrPSc occurs under detergent conditions that cause raft disruption and enhance the aggregate state of PrPSc.
Thus, these studies reported the significant enhancement of efficiency of SRH in clot lysis of platelet rich clots, and it may be concluded that SRH targets the platelet rich clot due to the direct selective binding to the activated platelet through GPIIb/IIIa receptor at the platelet rich thrombus and enhances the thrombolytic activity.
Enhanced in vivo potency of anti-HIV-1 bNAbs was associated with preferential engagement of activating, but not inhibitory FcγRs, and Fc domain-engineered bNAb variants with selective binding capacity for activating FcγRs displayed augmented protective activity.
Selective binding of nifedipine to amyloid fibrils.
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