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Developing strategies that produce more substantially enhanced secretion of GLP-1 would seem an essential ambition.
Thus, elevated levels of heparanase found in the plasma of diabetic patients may originate from enhanced secretion of heparanase by kidney and endothelial cells.
The enhanced secretion of LH was also maintained after i.c.v.
In this cohort of critically ill patients with type 2 diabetes, insulin therapy was associated with enhanced secretion of c-peptide in response to stress-induced hyperglycemia.
H1R knockout mice show enhanced secretion of Th2 cytokines and reduced severity of Th1-dependent autoimmune disease [58], pointing towards preferential Th1 activation by H1R.
Repeated cycles of oxidative injury by allylamine induce proliferative rat vascular smooth muscle cell (vSMC) phenotypes characterized by enhanced secretion of osteopontin (OPN).
Further differences between the two culture systems included enhanced secretion of leptin in 3-D tissue culture and differences in laminin expression (mRNA and protein level).
TAMs have higher pinocytic capacity, and enhanced secretion of pro-inflammatory cytokines [14].
Recently, Li and colleagues independently reported enhanced secretion of proteins of interest from P. pastoris after fusion to MBP [35].
In particular, the enhanced secretion of S100A8 and S100A9 was found in human prostate cancer cells [34], [35].
During sepsis the excess activation of C5 has been associated with enhanced secretion of pro-inflammatory mediators in response to TLR ligands such as LPS [55].
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