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This study is designed to explore the pathogenesis of schizophrenia by examining a large sample of young adults aged 16 25 years who are at enhanced risk of developing schizophrenia by having two close relatives with the disorder, and comparing them with matched controls.
Our findings are consistent with elevated SCN− contributing to an enhanced risk of developing pathologies associated with multiple inflammatory diseases.
Mutations in genes affecting GG-NER cause Xeroderma Pigmentosum (XP), characterized by severe photosensitivity and a more than 1000-fold enhanced risk of developing skin cancer.
(H EPATOLOGY 2012 56:1828–1837) High plasma total and low-density lipoprotein (LDL) cholesterol levels are linked to an enhanced risk of developing premature atherosclerosis.
Based on these findings, we conclude that loss of p53 tumor suppressor function in breast cancers leads to upregulation of Toca-1, and results in enhanced risk of developing metastatic disease.
Siblings of individuals with autism have a greatly enhanced risk of developing the condition, with a prevalence estimated to be >20 times in the general population (Ritvo et al., 1989; Lauritsen et al., 2005; Constantino et al., 2010).
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After adjusting for serum free testosterone and traditional risk factors of ED, arsenic exposure still enhanced the risk of developing ED (OR = 3.0; 95% CI, 1.0 9.2) in model IV.
There is a solid literature showing that some forms of electromagnetic radiation, such as that from power lines and electricity producing dynamos, can increase the deposition of amyloid and enhance the risk of developing Alzheimer's in humans.
Benzodiazepines, in particular, enhance the risk of developing acute brain dysfunction [ 6, 16- 18].
The severity of glomerular amyloid deposition enhances the risk of developing ESRD and increases the risk for premature death.
In people with chronic low-level aflatoxin exposure, this virus enhances the risk of developing liver cancer.
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