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Although the NIH report also focused on the need to adopt procedures that would lessen the administrative burden, it also concluded (p. 78) "Engaging more reviewers per application and throughout the review process will help to ensure review quality and consistency, as would enhanced reviewer training".
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To enhance the reviewer's inter-rater agreement, we evaluated 5 reviews (not included in the study sample) as a pilot testing of the database prior to starting the data abstraction process.
To enhance the reviewers' inter-rater agreement, we evaluated 20 papers (not included in the study sample) in a pilot test of the database prior to starting the data abstraction process.
Coding was reviewed and enhanced by a second reviewer (NJ).
We acknowledge the thoughtful comments and suggestions by the editor (Dr. Takuto Maeda) and the reviewer (Dr. Chung-Han Chan) and an anonymous reviewer that enhanced the quality of this manuscript significantly.
Reviewer#1: 1) The entire study is based on the interpretation of c-Fos labeling being enhanced upon enhanced discharge activity.
Authors also thank the anonymous reviewers who significantly enhanced the interpretation of our results.
Guidelines to establish quality in meta-analyses emphasize that inter-rater agreement of multiple reviewers enhances the validity of the data extracted and synthesized in systematic reviews [ 19, 44].
We appreciate this comment as it highlights an area of the Discussion that was unclear to the reviewer and we have enhanced the Discussion.
Pre-defined inclusion and exclusion ensured a robust study selection procedure, further enhanced by the engagement of two reviewers in the selection process.
No-one thinks that the web would be enhanced by a panel of formal peer reviewers who verify each piece of content before it was allowed to be posted on the web.
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CEO of Professional Science Editing for Scientists @ prosciediting.com