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The sg/sg mice also displayed significantly enhanced responsiveness to administration of intraperitoneal insulin, indicating enhanced whole-body insulin action compared with wild-type mice (Fig. 1f, g).
Inadequate affinity may limit the activity of introduced TCR, and engineering enhanced responsiveness to peptide MHC (pMHC) ligand is an important challenge [4].
(C ) Slo2.2 KO mice exhibit enhanced responsiveness to CQ injection.
The DTSQc shows enhanced responsiveness to change in these patients too.
Deficiency of Smpdl3b in macrophages enhanced responsiveness to TLR stimulation and profoundly changed the cellular lipid composition and membrane fluidity.
This corresponds to the clinical observations that PXR activation enhanced responsiveness to clopidogrel, whereas low polymorphic PXR expression correlates with clopidogrel non-responsiveness, suggesting that PXR represents a target to overcome resistance to clopidogrel treatment.
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The antidepressant appeared to enhance responsiveness to CM reinforcement.
Pravastatin enhances responsiveness to L-NMMA in the ocular microvasculature.
Diverse species respond to food scarcity by suppressing sleep and enhancing responsiveness to sensory cues, presumably to increase the probability of finding food [ 4- 6].
He indicated that a key practical issue is the need to develop means to convert ER-negative to ER-positive tumours to enhance responsiveness to hormonal therapy.
Gender-specific behavioural changes must be monitored to enhance responsiveness to groups at highest risk, and more research is needed on effective strategies to promote safer sexual practices.
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