Sentence examples for enhanced regression from inspiring English sources

Adoptive transfer of pmel-1 T cells genetically engineered with NFAT-murineIL12 (NFAT.mIL12.PA2) significantly enhanced regression of large established B16 melanoma.

RA treatment has inhibited transformation of human keratinocytes by HPV-16 [ 18] and has enhanced regression of cervical moderate dysplasia [ 19].

Furthermore, tumors of GLV-1h255 injected animals showed a significantly enhanced regression at 24 days p.i. when compared with PBS injected mice (p < 0.001), whereas the difference in volumes between GLV-1h68 and PBS treated tumors was also significant, but to a lesser extend (p < 0.01).

Using the enhanced regression model proposed here, it was possible to detect a trend of 20% over 20 years.

19, 39 Because the manifestation of melanoma as MUP does not alter BRAF or NRAS mutation frequency compared with melanomas with known primary site, some other genetic/immunological mechanism enhancing regression must be involved.

Treatment with compound 7b also significantly inhibited the growth of tumors and enhanced tumor regression in a paclitaxel-resistant HCT-15 xenograft model.

We demonstrate that oestradiol supplementation results in markedly enhanced tumour regression and that this is associated with raised levels of intratumoral IFN- γ.

Monden et al (1992) demonstrated that the intratumoral injection of the mixture of OK-432 and fibrinogen enhanced the regression of colorectal cancer, in which a granulomatous hypersensitive response containing many giant cells was generated in the tumour stroma.

They observed that small nanoparticles (diameter 1.9 14 nm), composed of gold or iron, enhance the regression of CT26 mouse tumours treated by fast protons (45 MeV-beam, pristine Bragg Peak, in the entrance, LET not specified).

Thus, appropriate, well-designed and fine tuned immune interventions that could resolve inflammatory responses and associated immunosuppression could enhance disease regression and reinforce successful responses to a given therapy.

Thus, tight glucose control during statin therapy may enhance plaque regression in patients with stable angina.