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The entwined relationship of ST2 signaling and AngII in cardiac hypertrophy/fibrosis coincides with our results demonstrating enhanced prognostic value of hyponatremia and elevated sST2 levels.
This study demonstrates that genetic diagnosis in neurodevelopmental disorders, including intellectual disability and common childhood seizure disorders, will have enhanced prognostic value and therapeutic relevance when coupled to multimethod phenotyping.
A clearly enhanced prognostic value of plasma mutations compared with tumour mutations was revealed when analysing the relationships between OR and DFS and the plasma KRAS mutation status (Table 2 and Figure 1).
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This may enhance prognostic value and provide mechanistic insights into how biological processes affect clinical phenotypes.
By using SFPA to separate different components, it is possible to enhance the prognostic value by selecting only the relevant components or genes for predictive purposes.
Boulier et al. specifically examined the role of TnI enhancing the prognostic value of CRP [ 17].
Incorporation of the PCT biomarker would enhance the prognostic value of these systems of risk stratification.
One large study did attempt multi-institutional validation but essentially failed to produce a robust, consistent signature, although the molecular data did appear to enhance the prognostic value of the clinical data available [138].
To the extent that cross-sectional risk factor associations differ, this may indicate that the different glycemic markers contribute independent clinical information and may enhance the prognostic value of standard glycemic markers.
Such a tool would enhance prognostic capability for clinicians and researchers.
If we hadn't ignored the conventional imaging findings (including diagnostic CT) when discordant with FDG PET/CT, the accuracy wouldn't have been enhanced and the prognostic value of FDG PET/CT incorporating a low dose, non-contrast CT wouldn't have been superior to that of conventional imaging.
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