Sentence examples for enhanced predisposition to from inspiring English sources

This enhanced predisposition to apoptosis could be deleterious for the central nervous system and could lead to increased neurodegeneration.

Because of the involvement of Polη in promoting error-free replication through cyclobutane pyrimidine dimers, its inactivation in humans causes the variant form of xeroderma pigmentosum, a genetic disorder characterized by a greatly enhanced predisposition to sun induced skin cancers [9], [10].

In conclusion, the GC-resistant polymorphisms ER22/23EK and 9 β are associated with an enhanced predisposition to develop RA.

The majority of patients with CAD + CKD in the current study had end-stage renal disease with an enhanced predisposition to accelerated atherosclerosis and, thus, would derive the greatest benefit from the statin therapy.

3 The group of atopic diseases comprises (besides AE) allergic rhinitis, conjunctivitis, asthma, and food allergy, all of which are characterized by an enhanced predisposition to develop sensitizations and allergies against natural antigens, derived from house dust mites, pollen, pets, or foods.

Given the important role of saliva in maintaining oral health, it is conceivable that alterations in salivary gland secretion and/or composition are liable to contribute to the markedly enhanced predisposition of this population to oral candidiasis.

Nucleosomes containing H4 K91A) have enhanced sensitivity to micrococcal nuclease digestion and a predisposition to disassemble at lower NaCl concentrations.

An important genetic component that enhances predisposition for the development of pancreatitis is emerging.

These findings suggest that sedentary lifestyle may enhance the predisposition to elevated adiposity, whereas greater leisure time physical activity may mitigate the genetic association [ 21].

For example, participants who know someone with AD will be aware of the devastation caused by the disease, thus enhancing their predisposition to support a tax-funded program of unrestricted access to AD medications.

Mice with hepatocyte-specific ablation of IKK β [ 50], NEMO [ 134], or with overexpression of an I κB α superrepressor [ 7] showed increased cell death, enhanced compensatory proliferation, predisposition to malignancy, and increased tumor susceptibility.