Sentence examples for enhanced pathway from inspiring English sources

To identify common pathways between complex diseases, we annotated gene-phenotype relationships found in the Genetic Association Database (GAD) [ 1] (see Additional File 1), then analyzed these phenotype-associated gene lists using the Structurally Enhanced Pathway Enrichment Analysis (SEPEA) algorithm (See methods for summary and described in detail in [ 13]).

Thus, enhanced pathway suppression that is induced by the combined targeting of PI3K and MEK pathways in TRP GBM cells was predictive of in vivo tumor growth inhibition.

The enhanced pathway representations have been successfully used to map SNP abundance data to individual nucleotide-sugar biosynthetic genes in the PGDB.

Resources and tools are continuously added or expanded to offer more comprehensive pathway data sets as well as enhanced pathway data manipulation, exploration and visualization capabilities.

We also used a method known as "structurally enhanced pathway enrichment analysis" (SEPEA_NT3) (Thomas et al. 2009), which incorporates the associated network information of KEGG (Kyoto Encyclopedia of Genes and Genomes) biochemical pathways (Kanehisa and Goto 2000; Kyoto Encyclopedia of Genes and Genomes 2000).

We did not attempt in this report to indicate explicitly the intracellular orientation of the multiple domains of enzymes in the enhanced pathway representations implemented in the prototype Populus PGDB; our assignment of sub-cellular localization of enzymes in pathway diagrams was intended to portray the site of catalytic activity.

Most of the enhanced pathways involve amino acid metabolism such as glycine, serine and threonine metabolism.

Valley formation in Susquehanna County has been associated with a greater density of fractures and lineaments, which likely serve as enhanced pathways for both water and gas migration.

To understand how field TP locusts respond to the high-altitude environments, we identified the significantly enhanced pathways in field-collected TP locusts (Additional file 2).

Recent studies have shown that differential use of pathway components enhances pathway specificity, facilitates signal integration and confers output selectivity.

InnateDB also enhances pathway-specific networks providing a more comprehensive picture of pathway signalling than traditional pathway diagrams.