Sentence examples for enhanced locus from inspiring English sources

Besides single nucleotide polymorphisms (SNPs), enhanced locus expression can drive decreased drug sensitivity, a phenomenon well documented for pfmdr1, where gene duplication events are strongly associated to mefloquine (MQ) resistance [22], [23] and lumefantrine decreased sensitivity [24].

GAL has been reported to modulate serotonergic and noradrenergic circuits [ 106] as well as GAL transmission (related to the inhibition of dopaminergic neurons in the ventral tegmental area) mediating anhedonia and reduced locomotor activity in depressed patients enhanced locus coeruleus (LC) hyperactivity [ 107].

This could explain why the Eae39 locus was not found in previous EAE and CIA experiments with B10.RIII/RIIIS/J crosses, where the number of mice did not allow for the density of genetic recombinations needed to reveal a disease protecting or enhancing locus [ 8, 14].

Distribution of yield enhancing loci among these diverse cultivated lines would also be helpful in pyramiding of QTLs with relatively higher contribution to the value of trait related to yield.

In Escherichia coli, homologous recombination is enhanced around loci coding for surface antigens, thereby increasing the effectiveness of recombination while minimizing its cost [ 32].

The authors propose that the presence of job autonomy and skill utilization in work can enhance internal locus of control, both directly and indirectly via job satisfaction.

We show that although the altruistic trait is being selected against, when it is genetically linked to productivity enhancing loci altruism can invade.

We demonstrated analytically that (a) the infection polymorphism between populations is stabilized by local adaptation, (b) gene flow between the populations is reduced but divergence at a selected locus enhanced, and (c) unidirectional CI selects for premating isolation in a mostly uninfected island population receiving migration from a Wolbachia-infected mainland.

Notably, the H3K9me2 amount was substantially enhanced in the locus defined by Primer #9 in the transgenic KYP overexpression plants.

Our previous transcriptome analysis revealed significant variations between autotetraploid and diploid rice hybrids harboring triple pollen sterility loci (SaSbSc) interactions, and we found that polyploidy enhanced F1 pollen sterility loci interactions that increase meiosis abnormalities and pollen sterility in autotetraploid rice (Wu et al. 2015).

A more recent study showed that targeting a CAR to the TRAC locus greatly enhanced the antitumor activity by reducing tonic activation (Eyquem et al., 2017).