Sentence examples for enhanced levels of dna from inspiring English sources

In support of the in vivo data, As exposure decreased ERCC1 mRNA expression and enhanced levels of DNA damage after a 2-AAAF challenge in cell culture.

The CSC model has clinical implications, in that CSCs have been known to contribute to radioresistance predominantly through enhanced levels of DNA repair activity and slow cell cycle kinetics.

Pretreatment with alpha-tocopherol succinate (vitamin E) resulted in a decrease of DNA single-strand breaks produced by Na2CrO4, while similar treatment with riboflavin (vitamin B2) enhanced levels of DNA breaks.

Consistently, SpTORC2-Gad8 mutants were synthetic lethal with loss of either S. pombe Rad52 or Rad51, possibly indicating that SpTORC2-Gad8 mutants incur an enhanced level of DNA damage that renders them dependent on HR.

The phenotypes in MEFs are correlated with the findings in Mdr2 −/− mice in which were observed enhanced levels of lipid peroxidation and DNA damage in the liver and increased susceptibility of carcinogen-induced tumor development in the intestine.

This might explain how increased oxidative metabolism in rapamycin T cells did not result in enhanced levels of ROS, which could cause DNA damage and cell death [60], [61], [62], [63], [64], [65], [66].

This study was designed to evaluate in dogs the ability of different methods of a single-dose DNA vaccination to elicit enhanced levels of neutralizing antibody.

The leukemic cells showed strongly enhanced levels of cS5F tetramers but unchanged cS5F dimer levels in a DNA binding assay.

Hence as both molecules are constitutively expressed in SKGT4 cells, the enhanced levels of JunB induced by DCA might potentially have a negative effect on c-Jun DNA binding.

Enhanced levels of intrinsic oxidative stress have been shown to induce a broad spectrum of oxidative damage of biomolecules including DNA, proteins and lipids [ 7].

The enhanced levels of soluble collagen in control group 69 days post infection were not observed on mice vaccinated with DNA-Sm14 or with both vaccines, indicating that vaccination with DNA-Sm14 alone or combined with DNA-Hsp65 decreases the extracellular matrix machinery, leading to the enhancement of tissue preservation.