Sentence examples for enhanced lethality from inspiring English sources

We hypothesized that if loss of LERP impairs lysosomal activity, further impairment due to chloroquine exposure would enhance the lysosomal defect and result in enhanced lethality.

Integrated guidance-autopilot systems are expected to result in significant improvements in missile performance, leading to lower weight and enhanced lethality.

Basically, these knockout mice were characterized by lower blood pressure and an enhanced lethality to endotoxin shock [13], [14].

The enhanced sensitivity of some diploid deletion strains to DOX when compared to the isogenic haploid strain may indicate that alterations in mating type expression patterns in the diploid may be responsible for the enhanced lethality.

Down-regulation of MCL1 through inhibition of translation has been clearly associated with enhanced lethality in Jurkat cells [ 46].

Whether these factors account for the enhanced lethality of LUJV and LASV infection in these animals will require further inquiry.

PARP inhibitors also enhance lethality in XPA-deficient cells after UV irradiation [ 55].

We conclude that only RPS3A is directly affecting αSyn toxicity, whereas PSMA2 is a suppressor of the αSyn-sensitivity in the cog6Δ background and the C-terminus of Spire homologue 1 enhances lethality in cells that are challenged with various stresses, but not specifically αSyn-induced lethality.

MIF enhanced the lethality of mice exposed to lipopolysaccharides and neutralization of MIF protected mice from the lethality of lipopolysaccharides [ 17, 18, 19].

In addition, it was found that small interference RNAs (siRNA) for Lig4 efficiently enhanced cell lethality induced by TMZ in human glioblastoma A172 cells.

Sorafenib enhanced the lethality of (SAHA + GST-MDA-7) in short-term cell death assays in RCCs (Fig. 4A).