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The upregulation of mitochondrial processing peptidase β subunit (L109) in Mg-deficient leaves (Table 1) agreed with the increased requirement for removing the "transient" targeting information due to enhanced import resulting from the increased abundance of the putative mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein (L87, Table 1).
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The diet, based on locally grown produce, was enhanced by imported spices, readily available due to the country's position at the crossroads of east-west trade routes.
Further, LC8 has been shown to enhance nuclear import of both the Rabies P protein and the p53 binding protein 53BP1 [12].
In mammals, insulin signaling functions to enhance glucose import in skeletal muscle and adipose tissue [ 24, 35].
Yuan et al. (2012) showed that B6 is one of, if not, the most long-lived inbred strains, enhancing the import of the observed 11% increase in B6 lifespan by IGF-1R+/− mutation.
Tom70 was previously shown to enhance the import of a few precursors containing N-terminal cleavable targeting signals (Hachiya et al. 1995; Hines et al. 1990; Hines and Schatz 1993; Schlossmann et al. 1994).
Our strategy of using IBB sequence to enhance nuclear import of plasmid DNA was not demonstrated probably due to the propensity of IBB to interact non-specifically with irrelevant proteins.
For example, parkin interacts with SUMO-1 (small ubiquitin-related modifier 1) and this association appears to modulate the activity of parkin as well as enhancing the import of parkin into the nucleus [ 77].
Our hypothesis states that the stronger coordination bonds between the Mg atom in chlorophyll b and chlorophyll c and amino acid sidechain ligands in chlorophyll a/b- and a/c-binding apoproteins, respectively, enhance their import into the chloroplast and assembly of light-harvesting complexes.
In fact, as a tasting of the life-enhancing imports now arriving from the top vineyard regions of South America proves, the exceptions are starting to rule.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com