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S. mutans is a critical microorganism associated with the pathogenesis of dental caries [2]. Figure 2A shows that the number of S. mutans colony forming units was ∼20 fold higher in the ΔF508 mice, correlating with the enhanced frequency and severity of caries lesions in these animals.
Since nbs1 homozygotes did not display any anaphase bridge under microscopic evaluation, markedly enhanced frequency and accelerated occurrence of anaphase bridges observed in our double homozygotes can only be explained by the synergistic interaction of both deficiencies.
Although looped tails, occasional spina bifida aperta and a low frequency of defective cochlear hair cell orientation are all found in Vangl2 Lp/+ mice (Copp et al., 1994; Yin et al., 2012), we detected a much enhanced frequency and severity of this phenotypic combination in compound Sdc4 Vangl2 mutants.
Therefore, it would be interesting to identify the molecules mediating this interaction between Treg and APCs to gain better understanding the mechanism by which enhanced frequency and functions of Treg are consistently induced, thus maintaining potent immunosuppressive microenvironment at cancer patients' tumour sites.
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Serine and threonine exhibit enhanced frequencies and α-helical propensities at the C-termini of α-helices because of their ability to function effectively as C-caps via their hydrogen bond donor capabilities in bonding to exposed amide carbonyls.
In aged mice, priming with AdC68NP followed by a booster immunization with A/X31 also markedly enhanced frequencies and numbers of NP-specific CD8+ T cells in blood and lungs, which further increased in lungs following A/PR8 challenge.
This causes the enhanced frequency of oscillations and hence the larger phase velocity.
With respect to HDs, M/DSFT patients displayed an enhanced frequency of gMDSCs and an increased number of neutrophils in the blood, number that matched the higher plasma arginase activity.
The first technique is the enhanced frequency domain decomposition (EFDD) and the other is the stochastic subspace identification (SSI).
Osrecql4 mutant plants showed hypersensitivity to DNA damaging agents and enhanced frequency of HR compared to wild-type (WT) plants.
Bcl2, an anti-apoptotic molecule and oncoprotein, effectively inhibits the endonuclease activity of mitochondrial APE1 (mtAPE1), leading to significant retardation of mtDNA repair and enhanced frequency of mtDNA mutations following exposure of cells to hydrogen peroxide (H2O2) or nitrosamine 4- methylnitrosamino -1- 3-pyridyl -1-butanone 4- methylnitrosamino -1- 3-pyridyl -1-butanone 4- methylnitrosamino -1- 3-pyridyl -1-butanone 4- methylnitrosamino -1- 3-pyridyl -1-butanone 4- methylnitrosamino -1- 3-pyridyl -1-butanone 4- methylnitrosamino -1- 3-pyridyl -1-butanone 4- methylnitrosamino -1- 3-pyridyl -1-butanone
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com