Sentence examples for enhanced destabilization from inspiring English sources
The latter has been predicted to be due to aberrant prediction error resulting in enhanced destabilization of beliefs.
An additional possibility, that cannot be ruled out on the basis of the SAXS data given the low resolution of the technique, is that the disruption of the closed state by Gdn-HCl may be enhanced through destabilization of the zinc finger structure by the denaturant, as this would result in only minor changes in the scattering profile.
Our results are consistent with the hypothesis that oligomerization of fusogenic peptide promotes membrane fusion, possibly by enhancing localized destabilization of lipid bilayers.
In general, miRNAs bind imperfectly to the 3′ UTR of target mRNA and block their expression by directly inhibiting the translational steps and/or by enhancing mRNA destabilization.
Maytansinoids inhibit tubulin polymerization and microtubule assembly and enhance microtubule destabilization, so there is potent suppression of microtubule dynamics resulting in a mitotic block and subsequent apoptotic cell death [ 7].
Similar results were obtained when chitosan is used as a coagulant by Jill et al. 1999, in their experiments where they stated that the destabilization of particles was enhanced by the increase in charged groups followed by charge neutralization, resulting in a decrease in optimum dosage.
Therefore, the introduction of the designed interchain disulfide bond enhanced the thermostability of FabΔSS and mitigated the destabilization caused by partial reduction of the interchain disulfide bond at the C-terminal region, which occurs in site-specific modification such as PEGylation.
Conformational mobility of the RCL is clearly enhanced in the transition state of the irreversible step, as shown by its destabilization in the presence of the 283 361 and 292 339 disulfides.
In vitro fluorescent microscopy and flow cytometry analysis demonstrated that PFV containing PEG-ceramide C14 provided enhanced intracellular delivery of FITC-labelled antisense ODN compared to PFV displaying faster or slower rates of destabilization (containing PEG-ceramide C8 or C20, respectively).
