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MiR-138 enhanced cell migration and invasion by targeting enhancer of zeste homologue 2 (EZH2) in squamous cell carcinoma cell lines (41).
ECM protein coatings enhanced cell migration from liver explants cultured on PFPE or PDMS.
Under strong confinement, the cytoskeleton contractility, intracellular traction, and actin filament elongation are highly promoted, which result in enhanced cell migration along the patterns.
CLCb/Dyn1-dependent adaptive CME selectively altered EGF receptor trafficking, enhanced cell migration in vitro, and increased the metastatic efficiency of NSCLC cells in vivo.
Therefore, it may be reasonable to think that LPA-induced activation of ERK and enhanced cell migration is mediated through PAK1.
In this study, we found disorganized actin in the form of membrane ruffling and enhanced cell migration in LRP1-deficient (LRP1−/−) SMCs.
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Estrogen slightly potentiates both progestins-enhanced cell migration and invasion Moesin is required for these tasks, as its silencing results in reduced migration in the presence of progestins.
Therefore we addressed whether p130Cas-enhanced cell migration could be attributed to an enhanced rate of membrane protrusion at the leading edge.
CAV1 silencing in ECC inhibits 4β-TPA-enhanced cell migration.
Since HER2 is also known to induce Akt activation and cell metastasis [ 29], we next investigated whether the increased HER2 expression mediated HBx-enhanced cell migration.
29, 30 PRL-3-enhanced cell migration is dependent on the preservation of its catalytic function, and the consensus phosphatase motif will potentially be a therapeutic target.
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CEO of Professional Science Editing for Scientists @ prosciediting.com