Sentence examples for enhanced cell cycle from inspiring English sources
This may also be the reason that both the formulations of CNPs showed greater apoptosis and enhanced cell cycle arrest than the native DOX at the same concentration, which further corroborated the results of the cytotoxicity assay (Figs. 5 and 6).
Additionally, a nuclear compartment and enhanced cell cycle and cell death subnetworks should be added to the model.
Moreover, small interfering RNA-mediated down-regulation of DKK3 enhanced cell cycle progression and disrupted three-dimensional acinar morphogenesis in RWPE-1 prostate epithelial cells [74].
In addition, both selective EGFR inhibitor AG 1478 and selective MEK inhibitor PD 98059 can block expression of pERK and CDK2, and prevent versican G3 enhanced cell cycle entry and cell growth.
The proliferation signature was distinct from the protein synthesis network, and although both increased during disease progression, they did so at different stages [43], consistent with the idea that enhanced cell cycle progression and enhanced cell growth may reflect different initiating events.
Combined SSd and radiation treatment also further enhanced cell cycle arrest than exposure alone.
This observation suggests that CA occurs by several rounds of duplication resulting in numerous mother centrioles with extra daughter centrioles, perhaps during an enhanced cell-cycle arrest.
The phenotypes resulting from ubc gene RNAi were compared between wild-type and ubc-25 (ok1732 ) mutant animals to determine whether the loss of two ubc activities produced an enhanced cell-cycle quiescence phenotype (Table S5).
Treatment of pancreatic cancer BxPc-3 and Panc-1 cells with α -mangostin resulted in loss of cell viability, accompanied by enhanced cell apoptosis, cell cycle arrest at G1 phase, and decrease of cyclin-D1.
As shown in Figure 5c, activation of the Akt or p38 pathway significantly decreased cell number in G0/G1 phase, whereas inhibition of these pathways enhanced cell G0/G1 cycle arrest by the combination treatment.
Several studies have shown that enhanced invasiveness, cell cycle progression and tumorigenicity can be conferred by overexpressing PEA3 in breast or lung cancer cell lines [43], [56], [83].
