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Enhanced breadth of priming is achieved through the use of primers and probes containing 5-propynyl deoxycytidine and deoxyuridine nucleotides that offer increased affinity and base pairing selectivity (18, 19 ).
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However, the mechanism behind the enhanced breadth appears different from a linear increase in recognition of epitopes due to increased-coverage of the viral diversity found among circulating HIV-1-B sequences.
The IFNγ response induced by peptide loaded DC was mediated by CD8+ T cells, with purified CD8+ T cells exhibiting an enhanced magnitude and breadth of IFNγ responses relative to PBMC.
>> To explore the breadth of enhanced potency of TH-302 by the addition of Chk1 inhibitors, other human cell lines were also investigated.
Clinicians' enhanced understanding of the wider determinants of health and their greater breadth of knowledge have been highlighted in other educational evaluations of public health master's programmes which cite broadening of how clinicians' view 'disease'[ 4].
Using directed evolution, enhanced green fluorescent protein (EGFP) was observed to tolerate residue deletion across the breadth of the protein, particularly within short and long loops, helical elements, and at the termini of strands.
The breadth of revolutionary improvements found in the Elite EX Series speakers include enhanced listening customization via treble contour controls.
The legume-specific, truncated EsDREB2B transcript is unique among DREB2 homologues in the breadth of transcriptional response and overexpression of the sequence in transgenic tobacco provides enhanced tolerance to osmotic-, salt-, cold- and heat-stress.
Limiting the availability of nutritious alternatives encouraged animals to learn to use different kinds of PSCs and enhanced diet breadth.
The present evidence of an enhanced response to the contingent visual tactile and visual proprioceptive cues may be interpreted in relation to the breadth of sensory stimulation provided.
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CEO of Professional Science Editing for Scientists @ prosciediting.com