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Because the abundance of γH2AX indicates the extent of DSBs, we first identified IR-induced dose-dependent H2AX-interacting partners and found that Bcl-2-associated transcription factor 1 (BCLAF1/Btf) showed enhanced association with γH2AX only under high-dose radiation.
The increase in the affinity was mainly attributed to an enhanced association rate.
f, Kinetic binding studies by biolayer interferometry reveal enhanced association rate and slower dissociation rate of ADI-15946 to GPCL compared to uncleaved GP.
Beyond the maximum of stress, while the solid-like gel structure is being broken down with time of shearing, the stress increases again by reflecting shear enhanced association of solid phase.
In the absence of PP1gamma1, both neurabins showed enhanced association with PP1alpha but not PP1beta.
We further found that HLY78 targets Axin-DIX and triggers the conformational switch of Axin from a "closed" auto-inhibitory state to an "open" active state, leading to an enhanced association of Axin with LRP6 and subsequent activation of LRP6.
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Individuals with elevated mean inflammatory markers exhibited enhanced associations with CRP, IL-6, and WBCs.
Birth order enhanced associations of socioeconomic status with central adiposity in young adult males from the Philippines (33).
Test for interaction between BMI and menopausal status was borderline significant (p = 0.08), indicating enhanced associations in post- and none in premenopausal women.
In addition, transcripts of Dcr1, Dcr2 and Drosha, which are involved in small RNA biosynthesis, exhibited enhanced associations with polysomes after P. falciparum challenge.
Enhanced associations between SO2 and CRP concentrations were observed among patients with a duration of diabetes <7 years and patients who were not treated with statin and TZD medication, reflected in significant interaction terms (Fig. 2).
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