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Only GSH supplementation suppressed enhanced aggregate formation in C. elegans bodywall muscle cells.
Second, animals with fluorescently-conjugated polyQ35 and polyQ40 had enhanced aggregate formation at two timepoints.
However, as aggregates of mutant AAT were also detected, e.g., in alveolar macrophages, enhanced aggregate clearance by autophagy might also be beneficial in the lung [30].
Thus, due to the enhanced aggregate interlock provided, concrete shear strength in the hybrid jacketed column similarly conventional steel jacketed column is larger than that in column with prestressing strands (FRP or SMA) only.
Because no differences on aggregate stability were observed between treatments, increments on soil organic carbon could not be related to biochar physical protection caused by aggregate formation or by enhanced aggregate stability.
An enhanced aggregate load upon expressing a dominant-negative hCul1 construct is also observed in cell culture, indicating that this effect of SCF complex on mutant huntingtin aggregates is not unique to the fly model.
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We highlight those strategies that promote targeted heterogeneity or homogeneity, and we describe approaches to engineer cell-particle and particle particle interactions that enhance aggregate stability and biological response.
High SWR not only causes problems in agriculture for prolonged irrigation and waste of water, but also might benefit soil by enhancing aggregate stability in post-fire, arid and seasonally dry ecosystems.
Shear forces created due to blood flow velocity gradients decrease when blood flow decreases, thus enhancing aggregate formation.
p62 has been shown to enhance aggregate formation (Donaldson et al. 2003; Wang et al. 2005; Komatsu et al. 2007; Gal et al. 2007; Nezis et al. 2008).
This work also demonstrates that, although at low micromolar concentrations, small nucleotides are not known to readily associate with heterocyclic intercalators (unlike polynucleotides), the circularization of dinucleotides appear to enhance aggregate formation.
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