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The conjugate of curcumin with demethylenated piperic acid in which methylenedioxy ring was open also shows enhanced activity than the corresponding piperic acid conjugate, emphasizing the role of free phenolics in the transport or in the binding processes.
Interestingly, most of the derivatives (8a l and 13a l) exhibited enhanced activity than their precursors (7a d and 12a d), which indicates that the combination of dithiocarbamate with β-carboline enhances the cytotoxicity of 8a l and 13a l.
The antioxidant activity of the compounds was also studied through scavenging effect on DPPH radicals with the copper complex showing enhanced activity than other compounds.
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Therefore, they exhibited significantly enhanced activity for CO oxidation than that prepared using PdCl2 as Pd precursor.
Enhanced activity is emphasized by bold numbers.
The Gln102Arg mutation reduces pyruvate activity by more than 8000-fold, whilenhancingng activity towards oxaloacetate by only 1000-fold.
CTBT enhances activity of several drugs [ 2].
ZrO2 with a monoclinic phase enhanced the activity than that with a tetragonal phase.
The Co- and Se-doped MoS2, display enhanced HER activity than pristine MoS2 with a low onset potential of 181 mV and 166 mV, and a low overpotential of 218 mV and 207 mV at a cathodic current density of 10 mA cm−2.
Interestingly, GC exerts enhanced antitumor activity than that of tRV (P < 0.05).
Alveolar macrophages from patients with COPD express more MMP-9 and have enhanced elastolytic activity than those from normal smokers or non-smokers [ 29, 32].
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