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These interactions significantly enhance the affinity of this MOF for unsaturated hydrocarbons.
Multiple ligand presentation is a powerful strategy to enhance the affinity of a probe for its corresponding target.
These approaches make it possible to quantify the importance of two major factors that combine to enhance the affinity of single carbohydrate-recognition domains (CRDs) for glycoprotein ligands by 100-to 300-fold.
It was found that a good rebinding solvent should have less affinity with both template and polymer and a good solubility, and a large self-association among solvent molecules could enhance the affinity between template and MIP.
The results of the present MD FEP simulation studies show that in order to enhance the affinity for the antigen, the engineering of HzKR127 should be made in such a way as to promote the dynamic stability of the overall protein conformation and that of the translational motion of the antigen in the antibody antigen complex.
In order to enhance the affinity of EC for basic surface of BAM and the resulting steric repulsion at the solid liquid interface, a portion of the hydroxyl groups in EC were substituted to the carboxylic acids via carboxylation of EC.
(iii) Substrate-loading from the SBP to the TMD dimer appears to enhance the affinity between the SBP and TMD (Rice et al., 2014).
Clustering of glycosides was reported to enhance the affinity for ASGPR and found to be in order tetraantennary > triantennary >> biantennary >> monoantennary galactosides (Connolly et al. 1982).
Csk and the cytoplasmic domain of phosphorylated Cbp form a stable complex and enhance the affinity of Csk toward Src (Takeuchi et al., 2000).
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Enhancing the affinity of scaffolds for endothelial cell (EC) is a crucial procedure for promoting angiogenesis in tissue engineering.
These two substitutions enhanced the affinity of p53 for specific DNA yet, counterintuitively, decreased the residency time of p53 on DNA.
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CEO of Professional Science Editing for Scientists @ prosciediting.com