Sentence examples for enhance repression from inspiring English sources

Taken together, our results show that Su z 2 interferes with auto-repression by Myc, but Su z 2 appears not to affect and possibly to enhance repression of other Myc targets.

These results suggest that ALT-PTK6 has a negative effect on growth in prostate cancer cells, which correlates with its ability to enhance repression of β-catenin/TCF regulated transcription (Figures 3 and 4).

We propose a model whereby in the context of normal cells, or in cancers that do not have abundant activated β-catenin, an up-regulation of TCF-4 would enhance repression of TCF/β-catenin responsive genes in conjunction with the other 1,25(OH 2D3-mediated β-catenin crOH 2D3-mediatedsly mentioned.

In combination with a zll mutation, which allows AGO1 greater access to miR165/166, increased levels of SQN in Ler-0 enhance repression of AGO1 targets, such as the Class III HD-ZIPs, and lead to a high frequency of terminal stem cell differentiation.

The presence of a poly(A) tail on target mRNA enhances repression, while blocking tail removal by deadenylation reduces the magnitude of translational repression.

NKX2-5∆HD had no activity alone, but significantly enhanced repression by ELK1 or ELK4, an activity not displayed by NKX2-5 WT.

Importantly, the ability of CP1 to protect TSC2 from AKT phosphorylation and enhance mTOR repression occurred in the absence of primary cilia, indicating that repression of mTOR occurs independently of CP1 localization to this organelle.

The increase in hfq expression might also enhance the repression of LEE and non-LEE gene expression, and thereby contribute to the reduced adherence phenotype in vitro.

Thus, as shown in Figure 7D, membrane-tethered CP1 enhanced TSC2 retention at the membrane and protected this tumor suppressor from AKT phosphorylation to enhance TSC2 repression of mTOR.

The sumoylation of Groucho has also been reported to enhance its repression activity.

This core machinery also associates with a TRIM-NHL protein, NHL-2, and a DEAD-Box protein, CGH-1, to enhance translational repression (64).