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These findings concluded that high porosity titanium scaffolds could enhance progression of hMSC/osteoblast differentiation and regulated osteoclast differentiation cooperating with osteoblast differentiation for calcification as compared with lower porous βTCP.
In chronic disease the effects of TXA2 largely promote tissue damage, especially in the heart where it may exacerbate myocyte apoptosis and enhance progression to dilated cardiomyopathy and heart failure, a major cause of death in patients with this disease.
As shown in the model in Fig. 4, reduced p53 activity in older p53 wildtype mice could enhance progression of oncogenically activated clones to malignancy, but this progression would not be nearly as rapid as in the somatically deleted p53F/F mice, where p53 loss is immediate and complete.
Damage to the podocytes, either directly in PHN or indirectly through mesangial injury in Thy 1.1 nephritis, may then interfere with the normal turnover function of meprin and may thus disturb the steady-state processing of GBM components and hence enhance progression of the disease.
Together, these results show that Bmi1 overexpression in GCPs at the levels achieved does not initiate medulloblastoma formation or enhance progression of preneoplastic lesions into tumours.
TNFAIP8 was also shown to interact directly with the Gα(i) receptor to enhance progression to oncogenic transformation (Laliberté et al., 2010).
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These regimens provide median survival times of 16 20 months [ 15, 20], and the addition of biologic agents, such as bevacizumab and cetuximab, to chemotherapy regimens may enhance progression-free survival (PFS) and overall survival (OS) [ 17, 21].
Two recent studies indicate that while the production of autophagosomes is enhanced, progression of the autophagic process is stalled leading to the accumulation of defective mitochondria in NPC1-deficient neurons,77, 78 raising the possibility that mitophagy is specifically a responsible phenotype.
TB enhances progression of HIV infection by inducing immune activation.
Results showed that gentamicin enhances progression of fructose induced metabolic syndrome.
Hyperuricemia is culminated in enhancing progression of metabolic syndrome and oxidative stress.
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