Sentence examples for enhance its potency from inspiring English sources

However, its chemical core does not allow a potential linkage to tumor-homing elements that could eventually enhance its potency.

In order to enhance its potency at AMPK and structure activity relationship study, GP derivatives were designed, synthesized, and evaluated in pharmacological AMPK activation assays.

The compound enhances its potency in vitro and reduces cell toxicity in vivo.

Further studies are ongoing to increase the affinity of ZRCM5 with the purpose of further enhancing its potency in bcr-abl expressing cells.

To enhance its oncolytic potency, we armed AdCB016 with p53 variant mp53(268N), which is resistant to HPV E6-mediated degradation.

One such ligand is Sonic hedgehog (Shh), whose posttranslational lipid modifications and assembly into multimers enhance its biological potency, potentially through receptor clustering.

Phosphorylation of GATA4 can enhance its DNA-binding potency and increase expression of GATA4-regulated transcripts.

To enhance its stability and neutralizing potency, a disulfide-stabilized scFv, ds-FV57, was also derived by introduction of cysteines at VH44 and VL100.

A further cyclization of linear peptide VT18-CAKKLV by adding a disulfide bond across its two strand arms, which results in a cyclic peptide cVT18-CAKKLV (charge = +3), can effectively stabilize the peptide β-sheet conformation in lipid, thus improving its membrane compatibility in second phase and enhancing its antibacterial potency (MIC = 35 67 μg/ml).

In addition, AKAP13 has been described to interact with ERα, enhancing its transcriptional potency [ 45].

Our findings imply that modification on 3-OH of trimethoxyflavonol can further enhance its in vitro anti-proliferative potency and PC-3 cell apoptosis induction.