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Further examination of IKKα using gene therapy or compounds that selectively enhance its functions in vivo is worthy of investigation in HD animal models.
This suggests that it is highly conserved and may play an important role in Alu transcription or enhance its functions, especially when the A box and/or B box is not intact or deficient.
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Some scientists and authors have questioned the need and use of technology and advances in medicine that have been achieved in the past few decades allowing us to manipulate the human body in ways that not only repair it, but potentially enhance its function(s).
The microbiota play a critical role in maintaining the health of the epithelium: some bacteria, like the bifidobacteria and Lactobacillus plantarum (common in fermented vegetables), seem to directly enhance its function.
In conclusion, we report in this study that riluzole is transported by BCRP at the BBB level and can enhance its function.
To enhance its function must be to our gain!
HyperISGylation may greatly assist ISGylation studies and may enhance its function as positive regulator of Interferon-related immune responses or as anti-tumoral modulator.
In fact, small molecule stabilizers of PDCD4, that enhance its function as a tumor suppressor by inhibiting its degradation, are currently being developed due to its potential as a therapeutic target for numerous cancers.
For example, Pin1 has been reported to induce Cyclin D1 expression and enhance its function.
We next asked whether the other network side chains are needed for full R166 function and enhance its function through either or both aspartate residues.
Interestingly, over-expression of mtr1-YFP did not enhance its function, meaning over-expression did not decrease the microtubule dwell-time compared to wild type.
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