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ISIS-SMNRx is an antisense oligonucleotide designed to enhance inclusion of SMN2 exon 7 mRNA and increase the amount of functional SMN protein.
Areas subject to review and recommendations by this sub-committee relate to inclusiveness, with specific emphasis on evaluating existing resources and identification of new resources that might further enhance inclusion.
This document emphasized the promotion of contact in order to enhance inclusion of immigrants.
This base-solubilized sample remained soluble indicating it too has been sufficiently modified by acylation to enhance inclusion body solubilization.
The panel should use rotating staff resources of congressional lawmakers to enhance inclusion.
SG proteins might enhance inclusion formation related to these proteins as a result of their mutual associations.
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Furthermore, stable SPF45 overexpression in SKOV-3 cells induces enhancement of fibronectin 1 expression and regulates fibronectin 1 AS by enhancing inclusion of the EDA region into fibronectin transcripts [ 113].
The sequence CUCCUCUUCC within transcript generated from the human calcitonin/calcitonin gene-related peptide (CT/CGRP) gene also binds PTB but in this case it enhances inclusion of the adjacent exon 4 into the mRNA [23].
In agreement with our results, Stoilov et al. also found that compounds identified via HTS with a minigene reporter construct in HEK 293 cells were capable of specifically enhancing inclusion of exon 10 in endogenous transcripts of MAPT [36].
These results indicate that MeCP2 may be involved in the DNA methylation-dependent ASE inclusion events, and that it might function to enhance the inclusion of the ASEs.
In this study we concentrate on a specific small-scale project, an inclusive and multi-dimensional soccer project for male asylum seekers, intended to enhance social inclusion and labour market participation.
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