Sentence examples for enhance heart function from inspiring English sources

Thus, increased sarcolemmal Ca2+ cycling has the potential to positively affect many pathways in E-C coupling and may provide a means to enhance heart function.

The recombinant human NRG1 has been used in clinical trials to treat chronic heart failure in China and Australia (ClinicalTrials.gov identifiers NCT01131637, NCT01258387), in which it proved to enhance heart function and reverse remodeling.

Our pre-clinical studies demonstrated that G-CSF based stem cell mobilization in combination with genetic or pharmaceutical CD26/DPP-IV inhibition after acute myocardial infarction leads to improved cardiac homing of stem cells, enhanced heart function and increased survival.

Such remodeling enhanced heart function and induced cardiomyocyte proliferation in mice and pigs.

Unfortunately, results are not optimistic from the antioxidant interventions in terms of reducing infarct size or enhancing heart function [ 68].

Although there have been several basic research and numerous clinical studies showing that different subpopulations of BM-derived stem cells and other progenitor cells are capable of enhancing heart function, the signaling pathways involved and the extent to which progenitor cells are able to reestablish cardiac function in stage IV HF is extensively debated.

The gene manipulated MSC-seeded peritoneum patch promotes tissue nutrition (angiogenesis), reduces myocardial remodeling, and enhances heart function after myocardial infarction.

Some preclinical studies have shown that DPP-4 inhibition after acute myocardial infarction improves cardiac homing of stem cells and enhances heart function [ 71].

By enhancing pump functions, global electricity consumption could be reduced by nearly 4%.

In a single-dose healthy volunteer study, modafinil, which diminishes brain GABA levels by noradrenergic stimulation of serotonergic neurons, enhanced heart rate responses and symptom scores during hypoglycemia and supported some aspects of cognitive function (53).

Therefore, differentiation of MiPS into cardiac progenitors (MiPS-CP) curtailed their tumorigenicity and significantly enhanced their engraftment capacity which led to reduced LV remodeling, attenuated infarct size and improved heart function.