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Clearly, targeted peptidomic analyses to profile related peptides can enhance elucidation of the events regulating complex and dynamic physiological processes responding to therapeutic agents.
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This work will enhance subsequent elucidation of the repertoire of miRNA expression in Boechera towards revealing the potential role of miRNAs in the switch from sexual to apomictic reproduction.
Hence, this version of activity-based probes enhances the elucidation of underlying mechanisms of disease pathophysiology and potential therapeutic intervention as analysis can reveal the intricate interplay between different signaling transduction pathways responsible for cellular function such as differentiation and apoptosis.
Such a marker would greatly enhance isocyanate research, including elucidation of exposure response relationships, and facilitate diagnosis and prevention.
Toxicogenomics offers the opportunity to enhance existing toxicity prediction strategies through elucidation of biological mechanisms around critical events.
Targeted strategies to further enhance the efficiency of the enzymes secreted include elucidation of regulatory mechanisms both at the promotor level (Mach and Zeilinger 2003; Schmoll and Kubicek 2003) as well as with respect to signal transduction (Schmoll et al. 2010).
The elucidation of functional physical interactions among different genomic regions would enhance our understanding of normal development properties and disease states.
Elucidation of the molecular mechanisms underlying radioresistance is crucial to enhance the efficacy of treatment and to improve the survival rates for NPC, which at present remain poor.
The elucidation of functional interaction between BMP antagonists and ID may enhance our knowledge about the molecular circuitry required for MC proliferation.
The key issue for the success of this approach is to find ways to induce or enhance the expression of cryptic or poorly expressed pathways to provide material for structure elucidation and biological testing.
Elucidation of the mechanism by which cellular contacts between pDCs and CD4+ T cells enhance antiviral activities of pDCs awaits future analysis.
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