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Intrapulmonary percussive ventilation physiotherapy with assisted autogenic drainage (IPV-AAD) is an emerging form of chest physiotherapy designed to enhance clearance of endobronchial secretions whilst enhancing alveolar recruitment.
Based on this evidence, we hypothesized that pharmacologic treatment with an inhaled beta-2 adrenergic agonist to enhance clearance of pulmonary edema from the distal airspaces would reduce donor hypoxemia and increase donor lung utilization.
An induction of CYPs via AHR signaling is to enhance clearance of these compounds.
Thus while brain CCL2 production may enhance beta-amyloidosis, peripheral CCL2 will enhance clearance.
Blocking CD200-CD200R interandion and stimulation of macrophage/microglia activation may enhance clearance of CNS myelin debris [36].
In contrast, IL-2 has been found to enhance clearance of Salmonella in the mouse raising the possibility that this cytokine is more important than IFNγ during the late response to Salmonella infection [77].
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Furthermore, rapamycin enhances clearance of pathologic proteins and thereby reduces their toxicity [ 46].
Fully established cellular senescence might not be easily reversible, further suggesting that short term caloric restriction enhances clearance of senescent cells by the immune system.
Biochemical analysis of rTg4510 mouse brain samples and T40PL cell lysates revealed that TFEB enhances clearance of only the hyperphosphorylated and misfolded Tau proteins.
Understanding how to keep balance of tau homeostasis may enable identification of potential mechanisms for enhancing clearance of pathological forms of tau.
In fact, experimental infection of mice with multiple strains of Salmonella has shown that MHC heterozygotes have enhanced clearance rates of infections, but this benefit was due to resistance being dominant rather than overdominant [ 4].
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