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It is appealing to envision engineering translation for the genetically encoded synthesis of new classes of molecules.
Special attention must be drawn to the mathematical reconstruction of bio-CAD model to facilitate the meshing process in the BEM environment and reduce the geometrical imperfections generated during the CAD to computer-aided engineering translation phase.
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The protocol combines PCR-based synthesis and engineering of translation templates with a combined transcription translation system.
Design recovery, software restructuring, forward engineering, language translation, platform migration, and code reuse can all be understood as transformations from one source text to another.
With the superior bioprinting speed, flexibility and scalability, this new prevascularization approach can be broadly applicable to the engineering and translation of various functional tissues.
The required process engineering for translation from laboratory scale devices to manufacturable large-area solar cells that can compete with bulk silicon solar cells and up-and-coming thin-film solar cells will be challenging.
Realizing the full potential of pig genetic engineering requires translation of the complete repertoire of genetic tools currently employed in smaller model organisms to practical use in pigs.
Alternatively, biophysical models have been developed to predict and guide engineering of translation initiation signals in bacteria, thereby providing an additional point of control.
Since most of the components have been worked out for pSer, future studies will focus on engineering orthogonal translation systems for pThr and pTyr.
We anticipate that improved knowledge of how exit tunnel proteins contribute to protein expression and folding could be key in the context of rationally engineering bacterial translation for efficient production of active, structurally complex proteins.
Furthermore, a patented technology, known as "Translation Engineering", demonstrated that better enhancement in translational efficiency is achievable by optimizing codon pair usage in addition to ICU optimization [ 21].
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