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Engineering obstacles also dimmed the early optimism.
Neither Hogarth nor Merritt believe there are any truly insurmountable engineering obstacles to digging a basement.
What is in between doesn't really matter except as a vector, a set of engineering obstacles to be overcome.
Some colleagues referred to him as a genius; he could attend to engineering obstacles with extreme focus, and was able to visualize simple solutions for intricate problems.
Plus there are all kinds of resolution and engineering obstacles.
Immunogenicity, difficult synthesis, and scale-up of these modifications are all engineering obstacles that stand in the way of expanding the use of these therapeutics.
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Here the route crosses the Sioux Narrows Bridge, the last part of the highway to be constructed and a formidable engineering obstacle in the 1930s.
In modern computational mathematics and engineering, the obstacle problems are not extremely difficult to solve numerically any more, as shown in numerous publications; see [8 14], for example.
For cell-sheet engineering, one major obstacle to sheet function is that cell sheets in suspension are fragile and, over time, will contract.
George Huebner Jr., Chrysler's director of research, became the turbine's chief proponent, and Sam Williams, an engineering genius, overcame technical obstacles during its development.
One of the major obstacles in engineering tissue constructs for clinical use is the limit of available human cells.
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