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Although a great diversity of metabolic engineering and adaptation approaches have been tested to boost xylose fermentation in biomass hydrolysates, yield and productivity of ethanol by genetically engineered S. cerevisiae strains are still much lower than those of glucose fermentation.
It is important to note that even without substantial metabolic engineering and adaptation, the Y35 strain performed similarly as the well-developed industrial benchmark 424A strain under certain conditions.
To overcome the challenge of bioconversion in the presence of inhibitory compounds, especially at high solids loading, a strain of Saccharomyces cerevisiae was subjected to evolutionary engineering and adaptation for fermentation of pretreated pine wood (Pinus taeda).
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Physico-chemical detoxification of HSSL, metabolic engineering and strain adaptation are possible strategies to improve the alcoholic fermentation efficiency in yeast species [4,7,18-20].
The result would be useful for xylanase engineering, and the adaptation mechanism to high alkaline was also discussed.
Genetic engineering and evolutionary adaptation to increase glycolytic flux coupled with transcriptomic and proteomic studies have identified targets for further modification, as have genomic and metabolic engineering studies in native xylose fermenting yeasts.
A large part of the research in swarm intelligence has focused on the reverse engineering and the adaptation of collective behaviors observed in natural systems with the aim of designing effective algorithms for distributed optimization.
In addition, genome shuffling has also been used in combination with metabolic engineering and evolutionary adaptation, for improving D-xylose utilization capacity in different S. cerevisiae strains [ 56, 57].
So do nuclear power, geo-engineering and environmental adaptation.
In order to cope with the increasing complexity of system design, component-based software engineering advocates the reuse and adaptation of existing software components.
However, the increasing level of global activities, the interactive nature of the Internet, and the global desire to share educational resources will surely be positive forces in improving the quality of available resources, thus facilitating teacher access and adaptation of engineering content in the PreK-12 engineering relevant education in schools.
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