Sentence examples for engineered to target the from inspiring English sources

FHV protein A was engineered to target the endoplasmic reticulum (ER) via a heterologous tobacco etch virus ER-targeting domain, and was expressed in cis or in trans relative to the replicating FHV RNA1.

To our knowledge, this is the first report demonstrating that oncolytic MVs can be engineered to target the lumenal endothelial surface of newly formed blood vessels when administered intravenously in living animals.

The latter SOFA-HDV ribozyme was originally engineered to target the hepatitis B virus (SOFA-HDV-RzHBV) [29].

Plants were also engineered to target the sensor proteins specifically to the cell nucleus.

Here, we report TALEs engineered to target the PU.1-14kb and Scl+40kb transcriptional enhancers as efficient new tools to perturb the expression of these key haematopoietic TFs.

To do so, we took advantage of an existing ZFN (ADH1-ZFN), which we previously engineered to target the ADH1 gene (At1g77120) at the end of chromosome 1 (Zhang et al. 2010).

In it, George Church and two collaborators integrated a CRISPR site engineered to target itself in the genome of human cells and calculated that it can store about 5 bits of information.

In a study published today in Nature Communications, Feng Zhang and colleagues at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT, with co-author Eugene Koonin at the National Institutes of Health, demonstrate that the new enzyme can be engineered to target and precisely nick or edit the genomes of human cells.

But she wasted no time wallowing in self-pity and turned immediately to the recommended treatment, which began with six months of chemotherapy: three months on Adriamycin and Cytoxan, followed by three months of Taxol, which was combined with a year on Herceptin, the drug engineered to target HER-2/neu HER-2/neu

Molecular imaging with novel radiopharmaceuticals engineered to target a specific subcellular process has the capacity to improve diagnostic accuracy and deliver enhanced prognostic information to alter management.

Thus, TALE DBDs engineered to target potentially methylated DNA targets may require the RVD N* in order to accommodate methylated cytosine or cytosine and therefore target a region in a state of dynamic methylation.