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Notably, a significant increase in anti-Fas/ActD killing as induced by JNK preactivation was observed in L929 cells which were engineered to suppress IκBα protein expression by antisense mRNA.
The epithelium in transgenic mice, which are engineered to suppress SMAD 3, exhibits accelerated reepithelialization, reduced inflammation, and reduced dermal fibrosis [ 137].
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Paricalcitol, a synthetic vitamin D analogue engineered to effectively suppress secretion of PTH with fewer hypercalcemic and hyperphosphatemic side effects, has been shown to effectively reduce PTH and also reduce proteinuria in recent studies in patients with CKD [ 4– 6, 12, 14, 16, 17].
"The idea would be to use mice genetically engineered to have suppressed insulin signaling, and then treat them with the drug rapamycin, which is well known to suppress the TOR pathway," Kapahi said. . . . . .
Servin, A. et al. A review of the use of engineered nanomaterials to suppress plant disease and enhance crop yield.
One new approach to pest management is the use of genetically engineered insects to suppress populations of their own species.
He had begun to realize, he says, that "the whole thing is a piece of patriarchal propaganda, engineered to consciously and deliberately suppress matriarchy".
He had begun to realize, he says, that "the whole thing is a piece of patriarchal propaganda, engineered to consciously and deliberately suppress matriarchy". He decided not to fight the words but, instead, to try to reveal in his drawings as much of domestic life as he could.
Furthermore, we have found that treatment with exogenous IL-4, in the form of DCs genetically engineered to produce IL-4, suppresses IL-17 and reduces the incidence and severity of CIA [ 21, 23].
By mutagenesis, ParM was further engineered to achieve strong discrimination against triphosphate binding and to suppress filament formation that occurs in the native protein.
In addition, studies have shown that hippocampal grafts of cell lines engineered to release GABA or other anticonvulsant molecules can suppress seizures.
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