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X-ray structures of the NRR regions from human Notch1 and Notch2, solved using polypeptides engineered to remove the S1 cleavage site, suggest that the S1 site of both receptors lies within a loop outside of the structural core of the HD domain [12], [13].
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The transcription factor B-Myb is present in all proliferating cells, and in mice engineered to remove this gene, embryos die in utero just after implantation due to inner cell mass defects.
Some of the mice are ordinary, but others have been genetically engineered to remove their ability to make IgE – so they can't get allergies.
An organic solvent-tolerant bacterium, Rhodococcus opacus B-4, was metabolically engineered to remove sulfur from dibenzothiophene (DBT), a component of crude oil.
Alternatively, for upregulation of a gene's expression level, epigenetic editing tools can be engineered to remove epigenetic repressive marks and/or induce activating marks at selected loci.
Prior to assuming the role of senior White House adviser under his father-in-law President Donald Trump, in 2012 Kushner directed a third party software engineer to remove the content, according to emails obtained by BuzzFeed News.
Green fluorescent protein (UV5) was re-engineered to remove native cysteine residues, and a new cysteine was introduced near the C-terminus, ∼20 Å from the native fluorophore, for site-specific attachment of chemical fluorophores.
The repair work is expected to take two days unless engineers have to remove the beam from the cargo bay to reach the faulty line.
As engineers worked to remove the faulty part, staff members sprang into emergency mode, offering passengers "comfort packs with water, blankets and glucose tablets," according to the spokeswoman.
The surgeon, Tatiana Zykova, discovered that two pieces of ferrite were lodged in the tube, and was able to remove one of them, whilst engineers were able to remove the other with a magnet.
A day after the name change was announced, Republican Georgia state Sen. Michael Williams blasted the organization for caving in to "left-wing social engineers who want to remove the concept of male masculinity from society".
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