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In this work, surface functionalization was engineered to regulate the interactions between a PCM of polyethylene glycol (PEG) and internal/external surfaces of a support of SBA-15 and the crystallization/stabilization behavior of PEG, and yield desirable thermal properties of the PEG confined in SBA-15 channels.
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Artificial transcription factors based on zinc finger proteins are engineered to regulate a variety of genes relevant to regenerative medicine such as a zinc finger transcription factor is designed to regulate the gene for vascular endothelial growth factor (VEGF).
Designer TALEs (dTALEs) are chimeric transcription factors that can be engineered to regulate gene expression in mammalian cells.
Water-soluble fullerenes can be engineered to regulate activation of mast cells (MC) and control MC-driven diseases in vivo.
Synthetic riboswitches are engineered to regulate gene expression in response to a variety of non-endogenous small molecules, and a challenge to select this engineered response requires robust screening tools.
Because numerous natural protein and RNA modules involved in c-di-GMP sensing have been discovered, various output modules can be engineered to regulate diverse biological activities by NIRW light.
The aim is to engineer instructive systems to regulate the spatio-temporal delivery of proper signalling based on the biological mechanisms of the different events that occur in the host microenvironment.
Here, we used engineered concave microwell arrays to regulate the size and shape of embryoid bodies (EBs)—cell aggregate intermediates derived from ES cells.
Engineers were pressured to regulate the water flow, not only for farmers but also for commercial fishers, who often requested conflicting water levels in the lake.
Accordingly, synthetic transcription factors can be engineered as a powerful tool to regulate the activity of a target gene promoter in mammalian systems, making it a useful approach for either basic research or therapeutic design.
Previously, RXR was engineered to be regulated by LG335, a synthetic inactive analog of the compound LGD1069 (also known as bexarotene, trade name Targretin®) [ 23, 24].
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