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Our results demonstrate that incorporation of the miR-122-MRE confers upon the DEN replicon an inhibitory susceptibility to miR-122 targeting, suggesting that DEN can be engineered to exert the desired replication restriction effect to avoid infection of vital tissues/organs.
We and others previously showed that proapoptotic ligands of the TNF family can be engineered to exert stronger antitumor activity by creation of single-chain molecules and by targeting death ligands to cell surface-expressed tumor antigens by fusion to a tumor-specific scFv.
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With cylinder bores held to tight tolerances and engineered to remain as round as possible in operation, the tension exerted by the piston rings can be reduced, lowering the drag as the piston travels through its stroke.
How he seemed faultlessly engineered to bat.
Engineered to be the best of Energy Star".
It is engineered "to lock in hydration".
Cotton — engineered to produce BT toxin.
Engineers are prepared to exert a tremendous amount of pressure to get the blowout preventer free, but they must be careful not to damage it because it is a key piece of evidence in ongoing investigations.
Perry has to exert himself to engineer a reunion between Schaeffer, who has surfaced from anonymity to defend himself from the mafia goon squads that have taken a sudden interest in him, and Elizabeth Waring, a hyper-vigilant honcho with the Department of Justice whose fondest desire is to turn Schaeffer into a government informant.
We speculate that evolution faced the question of how to exert efficient response to the environment: engineer new control proteins or make use of the conformational space of existing ones?
Wanderers continued to exert further pressure on the Engineers' goal and only Merriman's skill was able to prevent them from increasing their lead.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com